Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03107 |
Complement C5a Protein, Pig, Recombinant (His)
Complement C5a anaphylatoxin,C5 |
Sus scrofa (Pig) | P. pastoris (Yeast) |
Derived from proteolytic degradation of complement C5, C5a anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.... |